Welcome to the Fixler Lab at Tel Aviv University
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Publications
Selected Publications
The Fixler Lab develops quantitative optical methods for biomedical sensing, light–tissue interaction, diffuse reflectance, fluorescence lifetime imaging, and self-calibrated optical diagnostics.
Recent publications
Full Scattering Profile Optical Spectroscopy for Water Quality Assessment
This paper introduces an advanced optical spectroscopy technique utilizing the full scattering profile to evaluate water quality. By analyzing scattering signatures, the method offers a rapid, non-destructive, and highly sensitive approach for detecting pollutants and assessing environmental safety in real-time.
Endoscopic Iso-Pathlength Self-Calibration for Direction-Resolved Retrieval of Tissue Optical Properties
This study presents a novel endoscopic self-calibration method based on iso-pathlength points. The technique enables accurate, direction-resolved retrieval of tissue optical properties, significantly improving the reliability and precision of minimally invasive optical diagnostics in clinical settings.
Reduce Hypoxemia Overestimation in Pulse Oximetry Based on Iso-Pathlength: A Monte Carlo Study
Utilizing rigorous Monte Carlo simulations, this research addresses the critical issue of hypoxemia overestimation in standard pulse oximetry. By leveraging the iso-pathlength concept, the proposed model enhances the accuracy of blood oxygen saturation measurements in challenging diagnostic scenarios.
Impact of Analyzer Angle and Tube Geometry on the Iso-Pathlength Point in Polarization-Resolved Measurements of Scattering Media
This article investigates how analyzer angles and tube geometries influence the iso-pathlength point during polarization-resolved measurements. The findings provide essential design guidelines for optimizing optical setups to achieve a more precise characterization of complex scattering media.
A Self-Calibrated Single Wavelength Biosensor for Measuring Oxygen Saturation
This work details the development of an innovative, self-calibrating biosensor that measures oxygen saturation using a single wavelength. This simplified yet robust architecture reduces device complexity and cost while maintaining high diagnostic accuracy for continuous physiological monitoring.
Non-invasive Nanodiamonds Skin Permeation Profiling Using a Phase Analysis Method
We present a non-invasive phase analysis method to profile the skin permeation of nanodiamonds. This high-resolution technique allows for the precise tracking of nanoparticle diffusion dynamics through biological barriers, offering significant implications for advanced transdermal drug delivery systems.